[Clinical analysis of ovarian and cervical malignant lymphoma]

From Oct. 1980 to Oct. 1990, 456 cases with ovarian malignant tumor and 1,281 cases with cervical malignant tumor were admitted in our hospital. Among them, 7 were ovarian lymphoma and 3 were cervical lymphoma, accounting for 1.5% and 0.23% of ovarian and cervical malignant tumors respectively. According to the standard set up by Foxs, 5 were primary and 5 were metastatic in 10 lymphoma cases. Ovarian and cervical lymphoma were few, the primary cases were fewer. But its prognosis was better than the metastatic cases. The prognosis varied with the stages, the more advanced clinical stage, the high worse prognosis. The following condition indicates poor prognosis: rapid onset of abdominal symptoms; the presence of systemic symptoms; bone marrow infiltration; bilateral ovarian tumors; noncleaved cell pattern and cleaved-noncleaved cell mixture pattern; only treated with chemotherapy. Surgery was the first choice in the treatment of lymphoma. The typical operation on ovarian lymphoma was total hysterectomy, bilateral adnexectomy and omentectomy. The cytoreductive surgery which was used to advanced ovarian cancer was also proper for lymphoma, leaving the remained tumor 2cm in diameter, followed by introperitoneal and intravenous chemotherapy. The chemotherapy method was COP or COHP regimen. The treatment of primary cervical lymphoma was radical hysterectomy and pelvic paraaorta abdominal lymphodenectomy or radiotherapy. It seems that lymphoma was highly sensitive to radiotherapy. But radiotherapy was not proper for the metastatic cases because the affected areas were large. SLDH elevated in 5 cases of the 6 cases. It suggested that SLDH can serve as relative indicator for the diagnosis and prognosis of lymphoma.