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The MLLT3 gene maps between D9S156 and D9S171 and contains an unstable polymorphic trinucleotide repeat
G J Walker1, M K Walters, J M Palmer
1Queensland Cancer Fund Research Unit, Queensland Institute of Medical Research, Herston, Australia.
Genomics
|April 1, 1994
Abstract:
MLLT3, one of the genes shown to be a translocation breakpoint partner for the acute lymphocytic leukemia (MLL) gene, has been mapped to 9p22. We have identified a polymorphic trinucleotide repeat within this gene that shows somatic instability. The inheritance pattern of this polymorphism in recombinant individuals from families previously typed for other chromosome 9 markers indicates that the gene lies in the interval bounded by D9S156 and D9S171.