Complications of cutaneous cryotherapy

To review the complications and contraindications associated with cutaneous cryotherapy, and to describe the prevention of complications by appropriate technique, with consideration of the type of lesion being treated, the anatomical site and recognition of the high-risk patient.

We reviewed published work (in English) from 1982 to 1993. All commonly cited complications are presented and described.

Cutaneous cryotherapy generally has few complications. However, serious adverse events have been reported, and should be noted by all clinicians using cryotherapy. With adequate training, appropriate patient selection and the use of suitable cryotherapy regimens, cutaneous cryotherapy provides safe and effective treatment for a wide variety of cutaneous lesions.