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Open-angle glaucoma and older-onset diabetes. The Beaver Dam Eye Study
B E Klein1, R Klein, S C Jensen
1Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison 53792-3220.
Ophthalmology
|July 1, 1994
Summary
Older-onset diabetes is linked to a higher risk of developing open-angle glaucoma. This study found increased glaucoma rates in individuals with diabetes, highlighting a significant association.
Area of Science:
- Ophthalmology
- Endocrinology
- Public Health
Background:
- Diabetes mellitus is a growing global health concern.
- Open-angle glaucoma is a leading cause of irreversible blindness.
- The relationship between diabetes and glaucoma requires further investigation.
Purpose of the Study:
- To investigate the association between older-onset diabetes and open-angle glaucoma.
- To determine if diabetes increases the risk of developing open-angle glaucoma.
Main Methods:
- A population-based study of age-related eye disease involving 4926 participants.
- Evaluation for glaucoma using optic disc, visual field, and intraocular pressure criteria.
- Measurement of glycosylated hemoglobin levels and collection of medical history.
Main Results:
- Glaucoma rates were significantly higher in individuals with older-onset diabetes (4.2%) compared to those without (2.0%; P = 0.004).
- Including treated glaucoma cases, rates were 7.8% in the diabetes group versus 3.9% in the non-diabetes group (P = 0.0005).
Conclusions:
- The prevalence of open-angle glaucoma is elevated in individuals with older-onset diabetes.
- Older-onset diabetes is a risk factor for open-angle glaucoma.