[Immunologic and non-specific reactivity in patients with chronic suppurative obstructive bronchitis and its effect...

A total of 32 patients with aggravated chronic pyo-obstructive bronchitis were studied. Various immunological disorders and impaired non-specific responsiveness were detected in this group of patients. With this, abnormal T cellular immunity (reduced T cell counts at the expense of T helpers and their reaction to PGA) was the leading T cell immunity disorder. In the presence of the available immunity abnormalities, responses to inflammation (B-systems) and non-specific responsiveness were less pronounced. During treatment, the patients without substantial immunity disorders had normalized parameters of immunity and non-specific responsiveness, whereas the patients displayed this. The clinical efficacy of treatment was higher in patients without significant abnormalities in immunity and non-specific responsiveness.