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Published on: November 7, 2017
[Renal insufficiency due to cholesterol embolism. 4 cases]
R Cardelli1, L Gurioli, A Manzione
1Servizio di Nefrologia e Dialisi, Ospedale Maggiore di Chieri, Torino.
Insights
Atheroembolic disease, a complication of atheromatous disease, is often misdiagnosed due to a lack of specific tests. Consider it in geriatric patients with acute renal failure for better diagnosis and prognosis.
Area of Science:
- Nephrology
- Vascular Medicine
- Pathology
Background:
- Atheroembolic disease is a poorly understood complication of widespread atheromatous disease.
- Accurate diagnosis is challenging due to the absence of specific diagnostic markers.
Observation:
- The initial case was identified during a bladder biopsy in a patient with suspected carcinoma.
- Review of prior case histories revealed three additional cases within a two-year period.
Findings:
- Atheroembolic disease presents diagnostic challenges.
- The condition can be identified through histological examination, as seen in bladder biopsies.
Implications:
- Atheroembolic disease should be included in the differential diagnosis for acute renal failure in elderly patients.
- Early consideration of atheroembolic disease is crucial given its serious prognosis.
Abstract:
Atheroembolic disease is a complication of atheromatous disease and is quite often misunderstood. A precise diagnosis can be made difficult, by the lack of specific tests. The first case, in which we identified this disease, resulted from a bladder biopsy, in the instance of a patient with a suspected carcinoma. The experience, with this initial patient, led us to identification of a further 3 cases, within our previous 2 years case histories. One must consider the possibility of atheroembolic disease during the differential diagnosis of acute renal failure in geriatric patients, given the serious prognosis.
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