Related Experiment Video
Updated: Aug 10, 2026
Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
Published on: April 11, 2012
[Fibrous osteodysplasia in forensic medicine traumatology]
Abstract:
Histo- and ultrastructure of pathologically changed bone tissue in fibrous dysplasia was under study (9 cases were analyzed). Histologically a fibrous dysplasia focus is represented by cellular fibrous osteogenic tissue with scanty primitive coarse-fibrous bone structures. Ultrastructural changes evidence that these structures are formed at the edge of previous bone beams. Inadequate intraperiod fine structure of collagen fibrils does not provide a strong connection between hydroxyapatite crystals. These shifts result in functional inadequacy of bone tissue in fibrous dysplasia, that should be taken into consideration when assessing the severity of injury to osseous organs.
Related Concept Videos
01:29Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
01:27Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
01:29Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...