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Related Experiment Videos

Dermatofibrosarcoma protuberans: radiologic appearance

M J Kransdorf1, J M Meis-Kindblom

  • 1Department of Radiology, Saint Mary's Hospital, Richmond, VA 23226.

AJR. American Journal of Roentgenology
|August 1, 1994
PubMed
Summary
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Dermatofibrosarcoma protuberans typically appears as an unmineralized, nodular soft-tissue mass on imaging. Radiologic findings help characterize this rare tumor, differentiating it from higher-grade sarcomas.

Area of Science:

  • Radiology
  • Oncology
  • Dermatopathology

Background:

  • Dermatofibrosarcoma protuberans (DFSP) is a rare, slow-growing soft-tissue sarcoma.
  • DFSP originates from fibroblasts and typically presents as a superficial skin lesion.
  • Imaging characteristics of DFSP are not well-documented, leading to potential misdiagnosis.

Purpose of the Study:

  • To describe the radiologic appearance of histologically confirmed dermatofibrosarcoma protuberans.
  • To correlate imaging findings with clinical and pathological features of DFSP.
  • To aid in the differential diagnosis of soft-tissue tumors.

Main Methods:

  • Retrospective review of radiologic images from 11 patients with DFSP.
  • Analysis included CT scans, MR images, radiographs, bone scintigrams, and arteriograms.

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  • Patients' age, sex, and lesion duration were recorded.

    • Main Results:

    • All lesions were unmineralized, nodular masses in the skin and subcutaneous tissue (3-22 cm).
    • CT showed well-defined, lobular/nodular lesions with moderate enhancement.
    • MR findings were nonspecific with prolonged T1 and T2 relaxation times; arteriograms showed mild-moderate hypervascularity.

    Conclusions:

    • DFSP typically presents as an unmineralized, nodular soft-tissue mass involving skin and subcutaneous tissue.
    • CT and MR imaging are valuable for assessing lesion location, architecture, and relationship to adjacent structures.
    • Arteriography and bone scintigraphy can reveal hypervascularity and increased tracer uptake, respectively.