Adenosine in the termination of albuterol-induced supraventricular tachycardia
P Cook1, R J Scarfone, R T Cook
1Department of Emergency Medicine, Memorial Hospital, York.
Insights
Albuterol, a common asthma medication, can rarely cause supraventricular tachycardia (SVT) in children. Adenosine effectively treated this adverse reaction in a pediatric case, offering a new therapeutic option.
Area of Science:
- Pediatric Emergency Medicine
- Pediatric Cardiology
- Pharmacology
Background:
- Asthma affects 5% of US children, with status asthmaticus frequently requiring emergency care.
- Beta2-agonists, like albuterol, are standard emergency treatments for pediatric asthma exacerbations.
- Supraventricular tachycardia (SVT) is a potential adverse effect of beta2-agonist therapy.
Observation:
- A case report details a 4-year-old boy who developed SVT after receiving albuterol.
- This event occurred in a pediatric emergency department setting.
- The patient's SVT was successfully managed with adenosine.
Findings:
- This is the first reported instance of adenosine successfully treating albuterol-induced SVT in a child.
- Adenosine demonstrated efficacy in resolving the tachycardia.
- The case highlights a rare but significant adverse effect of a common asthma medication.
Implications:
- Clinicians should be aware of the potential for albuterol-induced SVT in pediatric patients.
- Adenosine may be a valuable treatment option for this specific iatrogenic condition.
- Further investigation into the recognition and management of SVT in children is warranted.
Abstract:
Five percent of children in the United States have asthma. Status asthmaticus is one of the most common conditions for which children seek care in a pediatric emergency department. beta 2-Agonists such as albuterol are the mainstay of emergency therapy for such children. We present a case of a 4-year-old boy who experienced supraventricular tachycardia (SVT) following albuterol therapy. This is believed to be the first report of adenosine being successfully used to treat a child with albuterol-induced SVT. We also briefly review the recognition and management of SVT in children and the pharmacokinetics of and indications for adenosine.
Related Concept Videos
Adrenergic Agonists: Therapeutic Uses
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and anaphylaxis:...
Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers
Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers
Antiarrhythmic Drugs: Class IV Agents as Calcium Channel Blockers
Verapamil, a calcium channel blocker, inhibits calcium movement across myocardial cell membranes and vascular smooth muscle. This results in the dilation of coronary and...
Cardiopulmonary Resuscitation IV: Pharmacological Management
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias


