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Development of direct antiglobulin reaction accompanying alloimmunization in a patient with Rhd (D, category III)

Vox Sanguinis
|January 1, 1975
PubMed

New examples of the Rhd (D, category III) red cell phenotype are described in three siblings. One of these individuals who had previously been transfused, received three units of Rho(D) positive blood several years later and developed a high titer anti-RhD antibody. This anamnestic response was associated with the development of an autoantibody which persisted for a period of at least 8 months. This observation represents another example of autoimmunization which has rarely been observed to accompnay alloimmunization.

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