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Intraorbital metastases

T Roşca1

  • 1Neurosurgery Clinic, Dr. G. Marinescu Hospital, Bucharest, Romania.

Romanian Journal of Neurology and Psychiatry = Revue Roumaine De Neurologie Et Psychiatrie
|January 1, 1994
PubMed
Summary

Intraorbital metastases, though rare, commonly present as exophthalmos. This study reviews ten histopathologically confirmed cases and three suspected cases of orbital tumors metastasizing to the eye socket.

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Area of Science:

  • Ophthalmology
  • Oncology
  • Pathology

Background:

  • Intraorbital metastases are uncommon occurrences in clinical practice.
  • Several primary tumor types frequently metastasize to the orbit, including breast, thyroid, prostate, spinocellular epithelioma, urinary bladder, and Ewing sarcoma.
  • Exophthalmos is the predominant clinical manifestation of intraorbital metastatic disease.

Purpose of the Study:

  • To present a series of intraorbital metastasis cases.
  • To highlight the clinical and pathological features of these rare orbital tumors.
  • To contribute to the understanding of metastatic patterns in the orbit.

Main Methods:

  • Retrospective review of ten histopathologically confirmed cases of intraorbital metastasis.
  • Inclusion of three additional cases with suspected orbital metastases based on clinical presentation and metastatic syndrome, despite non-confirmation during surgery.
  • Analysis of presenting symptoms, primary tumor origins, and surgical findings.

Main Results:

  • Ten cases of intraorbital metastasis were histopathologically confirmed post-operatively.
  • Three additional cases were identified as part of a metastatic syndrome, though not histopathologically confirmed intraoperatively.
  • Exophthalmos was the most common presenting sign across the evaluated cases.

Conclusions:

  • Intraorbital metastases represent a rare but significant clinical entity.
  • Prompt recognition and diagnosis are crucial for managing patients with suspected orbital metastases.
  • Further research into the management and outcomes of intraorbital metastases is warranted.

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