Orphan receptor HNF-4 and liver-specific gene expression

Lipopolysaccharide results in a marked decrease in hepatocyte nuclear factor 4 alpha in rat liver.

Hepatology (Baltimore, Md.)·2001

Novel nuclear target for thrombin: activation of the Elk1 transcription factor leads to chemokine gene expression.

Blood·2000

Analysis of protein dimerization and ligand binding of orphan receptor HNF4alpha.

Journal of molecular biology·2000

Modulation of transcriptional activation and coactivator interaction by a splicing variation in the F domain of nuclear receptor hepatocyte nuclear factor 4alpha1.

Molecular and cellular biology·1999

MODY1 mutation Q268X in hepatocyte nuclear factor 4alpha allows for dimerization in solution but causes abnormal subcellular localization.

Diabetes·1998

Proposed mechanism for the stabilization of nuclear receptor DNA binding via protein dimerization.

Molecular and cellular biology·1997

Beta 2-adrenergic receptor regulation of the cardiac L-type Ca2+ channel coexpressed in a fibroblast cell line.

Receptor·1995

Comparison of the in vivo rat brain regional pharmacokinetics of [3H]QNB, (R,S)-[125I]-4IQNB, and (R,R)-[125I]-4IQNB binding to the muscarinic acetylcholine receptor in relationship to the regional subtype composition.

Receptor·1995

Plasma membrane ATP receptors in Trypanosoma cruzi trypomastigotes.

Receptor·1995

Selective desensitization of beta 1- and beta 2-andrenergic receptors in C6 glioma cells. Effects on catecholamine responsiveness.

Receptor·1995

Effects of ET antagonists (PD143296 and PD145065) on contractions in guinea pig hilar bronchus induced by endothelin-1 and its related peptide.

Receptor·1995

Expression of functional muscarinic acetylcholine receptor subtypes in human corpus cavernosum and in cultured smooth muscle cells.

Receptor·1995

Mechanistic Study of ATP-Dependent Regulation of the Hrq1 Oligomeric State and Its DNA Unwinding Activity in Saccharomyces cerevisiae.

The Journal of biological chemistry·2026

Structural Maintenance of Chromosomes Complexes in Bacteria.

Annual review of microbiology·2026

3D genome organization in tissue regeneration involves long-range chromatin loops.

Science advances·2026

TALE and Hox Transcription Factors Modulate Adult Behaviors in Zebrafish.

Behavior genetics·2026

INSL3 Preserves Male Reproductive Function Under Inflammatory and Glucocorticoid Stress in Rats.

Reproductive sciences (Thousand Oaks, Calif.)·2026

Gene clustering drives the transcriptional coherence of disparate biological processes in eukaryotes.

iScience·2026

Related Experiment Videos

Orphan receptor HNF-4 and liver-specific gene expression

Related Concept Videos

Lipopolysaccharide results in a marked decrease in hepatocyte nuclear factor 4 alpha in rat liver.

Novel nuclear target for thrombin: activation of the Elk1 transcription factor leads to chemokine gene expression.

Analysis of protein dimerization and ligand binding of orphan receptor HNF4alpha.

Modulation of transcriptional activation and coactivator interaction by a splicing variation in the F domain of nuclear receptor hepatocyte nuclear factor 4alpha1.

MODY1 mutation Q268X in hepatocyte nuclear factor 4alpha allows for dimerization in solution but causes abnormal subcellular localization.

Proposed mechanism for the stabilization of nuclear receptor DNA binding via protein dimerization.

Beta 2-adrenergic receptor regulation of the cardiac L-type Ca2+ channel coexpressed in a fibroblast cell line.

Comparison of the in vivo rat brain regional pharmacokinetics of [3H]QNB, (R,S)-[125I]-4IQNB, and (R,R)-[125I]-4IQNB binding to the muscarinic acetylcholine receptor in relationship to the regional subtype composition.

Plasma membrane ATP receptors in Trypanosoma cruzi trypomastigotes.

Selective desensitization of beta 1- and beta 2-andrenergic receptors in C6 glioma cells. Effects on catecholamine responsiveness.

Effects of ET antagonists (PD143296 and PD145065) on contractions in guinea pig hilar bronchus induced by endothelin-1 and its related peptide.

Expression of functional muscarinic acetylcholine receptor subtypes in human corpus cavernosum and in cultured smooth muscle cells.

Mechanistic Study of ATP-Dependent Regulation of the Hrq1 Oligomeric State and Its DNA Unwinding Activity in Saccharomyces cerevisiae.

Structural Maintenance of Chromosomes Complexes in Bacteria.

3D genome organization in tissue regeneration involves long-range chromatin loops.

TALE and Hox Transcription Factors Modulate Adult Behaviors in Zebrafish.

INSL3 Preserves Male Reproductive Function Under Inflammatory and Glucocorticoid Stress in Rats.

Gene clustering drives the transcriptional coherence of disparate biological processes in eukaryotes.

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Orphan receptor HNF-4 and liver-specific gene expression

Related Concept Videos

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