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Expression and gene sequence of outer surface protein C of Borrelia burgdorferi reisolated from chronically infected
B Stevenson1, L K Bockenstedt, S W Barthold
1Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut 06520.
Infection and Immunity
|August 1, 1994
Abstract:
OspC from Borrelia burgdorferi reisolated from mice persistently infected with cloned spirochetes was examined. In all cases, the sequence of the ospC gene was identical to that of the original inoculant. We conclude that variation of ospC is not necessary for evasion of the host immune system.