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Cloning of Entamoeba genes encoding proteolipids of putative vacuolar proton-translocating ATPases
S Descoteaux1, Y Yu, J Samuelson
1Department of Tropical Public Health, Harvard School of Public Health, Boston, Massachusetts.
Infection and Immunity
|August 1, 1994
Abstract:
Molecular cloning techniques were used to identify genes encoding the proteolipids of putative vacuolar proton-transporting ATPases (V-ATPases; EC 3.6.1.35) of Entamoeba histolytica (Ehvma3) and Entamoeba dispar. The Ehvma3 gene encoded a 177-amino-acid peptide, with an M(r) of 18,110, which showed extensive positional identities with peptides of E. dispar (92%), Schizosaccharomyces pombe (58%), and humans (56%).