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Effects of meal intake on the flow velocity in the superior mesenteric artery: evaluation with 2D phase mapping MRI
T Masui1, H Isoda, T Mochizuki
1Department of Radiology, Hamamatsu University School of Medicine, Japan.
Objective:
Reliable results in MR flow measurements have been reported in humans. The current study was performed to evaluate the effects of a meal intake on the flow velocities in the superior mesenteric artery (SMA) and aorta by using 2D phase-mapping MRI.
Materials And Methods:
A constant flow phantom generating 0-150 cm/s of flow velocities was constructed to evaluate the accuracy of MR flow measurements. Eleven healthy volunteers underwent serial MRI once before and three times after a mixed meal intake (700 kcal).
Results:
Reliable MR flow measurements were validated in the constant flow phantom. In the healthy volunteers, the SMA and aorta had triphasic flow velocity waveforms in one cardiac cycle. Ingestion of a mixed meal increased flow velocities in the SMA. Peak velocities were observed at 20 min after the meal. The aortic flow velocities were unaffected by the meal.
Conclusion:
A 2D phase-mapping MR technique is feasible to evaluate the SMA and aortic flow velocities. Evaluation of the flow velocities in the SMA may contribute to understanding intestinal as well as hepatic conditions in humans.
Insights
Meal intake significantly increases superior mesenteric artery (SMA) blood flow velocities, but does not affect aortic flow, according to 2D phase-mapping MRI. This technique is feasible for evaluating flow dynamics.
Area of Science:
- Medical Imaging
- Cardiovascular Physiology
- Gastrointestinal Physiology
Background:
- Magnetic Resonance (MR) flow measurements have demonstrated reliability in human studies.
- Understanding blood flow dynamics is crucial for assessing organ function.
Purpose of the Study:
- To evaluate the impact of meal intake on flow velocities in the superior mesenteric artery (SMA) and aorta.
- To assess the feasibility of 2D phase-mapping MRI for measuring these flow velocities.
Main Methods:
- A constant flow phantom was used to validate MR flow measurement accuracy (0-150 cm/s).
- Eleven healthy volunteers underwent serial 2D phase-mapping MRI scans before and after consuming a 700 kcal mixed meal.
Main Results:
- MR flow measurements were validated using the flow phantom.
- In healthy volunteers, triphasic flow velocity waveforms were observed in both the SMA and aorta.
- Meal ingestion led to increased SMA flow velocities, peaking at 20 minutes post-meal.
- Aortic flow velocities remained unaffected by meal intake.
Conclusions:
- 2D phase-mapping MRI is a feasible technique for evaluating SMA and aortic flow velocities.
- Changes in SMA flow velocity following a meal may offer insights into intestinal and hepatic conditions.