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Sepsis caused by Flavimonas oryzihabitans
K G Lucas1, T E Kiehn, K A Sobeck
1Department of Medicine, Memorial-Sloan Kettering Cancer Center, New York, NY 10021.
Medicine
|July 1, 1994
Summary
Most central venous access device (CVAD)-related infections caused by F. oryzihabitans can be successfully treated with a 14-day antimicrobial course, often avoiding device removal. Complications may arise from polymicrobial infections or early antibiotic cessation.
Area of Science:
- Infectious Diseases
- Medical Microbiology
- Clinical Medicine
Background:
- Previous reports indicate significant complications, including device removal, for F. oryzihabitans sepsis associated with central venous access devices (CVADs).
- High rates of complications occurred despite broad-spectrum antimicrobial therapy and in vitro susceptibility.
Purpose of the Study:
- To evaluate the treatment outcomes of F. oryzihabitans sepsis in patients with CVADs.
- To identify factors influencing successful treatment and complications.
Main Methods:
- Retrospective case series analysis of 22 patients with F. oryzihabitans sepsis and CVADs.
- Review of treatment protocols, antimicrobial agents used, and patient outcomes.
Main Results:
- The majority of CVAD-related F. oryzihabitans infections were successfully treated with a 14-day antimicrobial course.
- Device removal was typically not necessary for successful treatment.
- Polymicrobial infections and premature antibiotic discontinuation were identified as complicating factors.
Conclusions:
- A 14-day course of antimicrobials with antipseudomonal activity is effective for treating F. oryzihabitans CVAD-related sepsis.
- Successful treatment can often be achieved without device removal.
- Careful management to avoid polymicrobial infections and ensure complete antibiotic therapy is crucial.