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Related Experiment Videos

Clinical evaluation of luteal function

S T Nakajima1, M H Molloy, R H Oi

  • 1Department of Obstetrics and Gynecology, University of California, Davis, Sacramento.

Obstetrics and Gynecology
|August 1, 1994
PubMed
Summary
This summary is machine-generated.

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Neither basal body temperature (BBT) charting nor a single midluteal serum progesterone level accurately predicted endometrial biopsy results. These common methods for assessing luteal function lack predictive power for endometrial receptivity.

Area of Science:

  • Reproductive endocrinology
  • Infertility diagnostics
  • Gynecological research

Background:

  • Assessing luteal function is crucial for diagnosing infertility.
  • Basal body temperature (BBT) charting and serum progesterone levels are commonly used methods.
  • The predictive accuracy of these methods for endometrial receptivity requires further investigation.

Purpose of the Study:

  • To evaluate the ability of luteal phase length (via BBT) and midluteal serum progesterone to predict endometrial biopsy outcomes.
  • To compare the predictive value of BBT charting versus serum progesterone levels.
  • To determine if combined assessment improves prediction of endometrial biopsy results.

Main Methods:

  • Retrospective analysis of 141 infertile women.

Related Experiment Videos

  • Luteal phase length assessed by BBT in one cycle.
  • Midluteal serum progesterone measured in a second cycle.
  • Endometrial biopsy performed in a third cycle for comparison.

    • Main Results:

    • No significant difference in in-phase or out-of-phase endometrial biopsy results across groups.
    • Groups were defined by luteal phase length (normal ≥11 days) and progesterone levels (normal ≥10 ng/mL).
    • Neither BBT-derived luteal phase length nor serum progesterone predicted biopsy outcomes.

    Conclusions:

    • Basal body temperature charting is not a reliable predictor of endometrial biopsy results.
    • A single midluteal serum progesterone level does not predict endometrial biopsy outcomes.
    • Current methods for assessing luteal function may not accurately reflect endometrial receptivity.