Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Further experience with pemphigus in children

A J Kanwar1, S Dhar, S Kaur

  • 1Department of Dermatology, Venereology, and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Pediatric Dermatology
|June 1, 1994
PubMed
Summary

Childhood pemphigus, including pemphigus vulgaris and pemphigus foliaceus, appears similar to adult cases. Dexamethasone pulse therapy showed positive results in young patients with pemphigus vulgaris.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Persistent facial discoid dermatosis successfully treated with topical calcipotriol.

Clinical and experimental dermatology·2021
Same author

Comparison of efficacy of cold trypsinization versus warm trypsinization in preparation of autologous non-cultured epidermal cell suspension for treatment of stable vitiligo.

Journal of the European Academy of Dermatology and Venereology : JEADV·2019
Same author

Subcornfal Pustular Dermatosis.

Indian journal of dermatology, venereology and leprology·2017
Same author

Survey of the causes of urticaria.

Indian journal of dermatology, venereology and leprology·2017
Same author

What is your diagnosis.

Indian journal of dermatology, venereology and leprology·2017
Same author

Peyroniie's Disease.

Indian journal of dermatology, venereology and leprology·2017

Area of Science:

  • Dermatology
  • Pediatric Autoimmune Diseases

Background:

  • Pemphigus is a rare autoimmune blistering disease.
  • Limited data exists on childhood pemphigus presentation and management.

Observation:

  • Seven pediatric patients diagnosed with pemphigus (six pemphigus vulgaris, one pemphigus foliaceus).
  • Four children with pemphigus vulgaris received dexamethasone pulse therapy.

Findings:

  • Treatment with dexamethasone pulses resulted in disease control.
  • No therapy-related complications were observed during 6-12 months of follow-up.
  • Pediatric pemphigus shares clinical features, disease course, and therapeutic principles with adult pemphigus.

Implications:

  • Dexamethasone pulse therapy may be an effective treatment for childhood pemphigus.

Related Experiment Videos

  • Findings support similar management strategies for pediatric and adult pemphigus patients.
  • Further research into childhood pemphigus is warranted.