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Management of suboptimal cytologic smears. Persistent inflammatory smears
N McLachlan1, J R Patwardhan, B Ayer
1Cytology Department, Westmead Hospital, Sydney, Australia.
Acta Cytologica
|July 1, 1994
Summary
Persistent cervical inflammation detected via cytologic smears often indicates significant abnormalities. Colposcopy is crucial for managing these findings, revealing high-grade squamous intraepithelial lesions (CIN 2) or worse in a notable percentage of cases.
Area of Science:
- Gynecologic Pathology
- Cervical Cytology
- Colposcopy
Background:
- Persistent cervical inflammation identified in cytologic smears warrants further investigation.
- Cytologic diagnoses require correlation with clinical findings for accurate patient management.
Purpose of the Study:
- To compare cytologic diagnoses with colposcopic and biopsy findings in women with persistent cervical inflammation.
- To evaluate the diagnostic yield of colposcopy in managing persistent inflammation.
Main Methods:
- Review of cytologic smears from 161 women with persistent inflammation.
- Comparison of cytologic diagnoses with subsequent colposcopic and biopsy results.
- Analysis of the proportion of advanced abnormalities detected.
Main Results:
- In 102 cases with available colposcopy data, 62.7% showed abnormal findings requiring treatment.
- Biopsy findings revealed abnormalities in 76.2% of 84 cases.
- High-grade squamous intraepithelial lesions (CIN 2) or worse were identified in 7.9% by colposcopy and 19.1% by biopsy.
Conclusions:
- Colposcopy is essential for managing persistent inflammation detected in cervical cytologic smears.
- The high detection rate of significant lesions underscores the importance of colposcopic evaluation.
- Prompt colposcopic assessment aids in identifying and treating advanced cervical abnormalities.