Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Plasma cell-rich thymoma

C A Moran1, S Suster, M N Koss

  • 1Department of Pulmonary and Mediastinal Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000.

American Journal of Clinical Pathology
|August 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Performance and environmental impact of egg production in response to dietary supplementation of mannan oligosaccharide in laying hens: a meta-analysis.

Poultry science·2022
Same author

Safety assessment of Asterarcys quadricellulare, a microalga, with applications in poultry and livestock feed.

Regulatory toxicology and pharmacology : RTP·2022
Same author

Toxicological evaluation of a glycan preparation from an enzymatic hydrolysis of Saccharomyces cerevisiae.

Regulatory toxicology and pharmacology : RTP·2021
Same author

Technical Innovation for Visual Assessment of Preterm Newborns in a Neonatal Intensive Care Unit: Exploratory Study.

Rehabilitation research and practice·2021
Same author

Toxicological evaluation of an unextracted Aurantiochytrium limacinum biomass, a novel docosahexaenoic acid rich feed ingredient.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2020
Same author

Heterotrophic <i>Aurantiochytrium</i> sp. supplementation to layer diets sustainably increases the omega-3 concentration of eggs.

British poultry science·2019
Same journal

Invasive urothelial carcinoma in association with surface low-grade papillary urothelial carcinoma: clinical and pathologic insights from a rare entity.

American journal of clinical pathology·2026
Same journal

CEACAM1 expression by immunohistochemistry in B-cell lymphomas and plasma cell myeloma.

American journal of clinical pathology·2026
Same journal

Comprehensive multicriteria life cycle assessment of biopsy processing in a surgical pathology department.

American journal of clinical pathology·2026
Same journal

Prognostic significance of Myb protein and its downstream target genes in lacrimal gland adenoid cystic carcinoma.

American journal of clinical pathology·2026
Same journal

Mismatch repair protein "nonclassic expression loss" pattern in colorectal cancer: an important staining pattern that is not well understood.

American journal of clinical pathology·2026
Same journal

Musculoskeletal pain in medical laboratory personnel: a cross-sectional study.

American journal of clinical pathology·2026
See all related articles

This study details a rare thymoma case with abundant plasma cells. The patient later developed unexplained hypergammaglobulinemia, suggesting thymus-related autoimmune modulation.

Area of Science:

  • Immunology
  • Oncology
  • Pathology

Background:

  • Thymomas are neoplasms of the thymus gland.
  • The thymus plays a crucial role in immune system development.
  • Anterior mediastinal masses can include thymomas.

Observation:

  • A 49-year-old woman presented with an anterior mediastinal thymoma.
  • Histology revealed a prominent plasma cell stromal component.
  • Immunocytochemistry showed polyclonal kappa and lambda light chains in stromal plasma cells.

Findings:

  • No initial signs of myasthenia gravis or autoimmune disease were present.
  • The patient subsequently developed polyclonal hypergammaglobulinemia of unknown etiology.
  • This suggests a potential link between the thymoma and immune dysregulation.

Related Experiment Videos

Implications:

  • This case may represent an extreme form of thymic immune modulation.
  • It highlights the potential for thymomas to influence B-cell compartment hyperplasia.
  • Further research is needed to understand the thymus-autoimmunity connection in thymoma.