[Lyme disease: a multisystemic condition]

While Lyme's Disease is clinically well known since 1920, its complete ascertainment and its etiological agent, as well as the details of its transmission mechanisms and multisystemic clinical manifestations (mainly dermatological, cardiac, neurological and articular) have been only recently known. In Spain, the number of papers published on this affection has increased lately, although its understanding is still not as generalized as it should be. This review focuses mainly on our country's experience, as well as on its clinical characteristics. We think that it is a very important affection, since its estimated incidence is 500 cases per year, a significant figure compared to other European countries.