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[Persistence of physiological hydrocephaly in newborns]
Insights
Persistence of physiological hydrocephalus (PPH) is a common finding in infants, affecting brain development. While not clinically significant itself, PPH can indicate minimal brain dysplasia and may predispose to hydrocephalus.
Area of Science:
- Neuroscience
- Pediatric Neurology
- Developmental Biology
Abstract:
During intratubal development of the brain the reduction delay of the fetal ventricular system is marked as persistence of the physiological hydrocephalus (PPH). PPH was revealed in 26.9%, 30.3% and 21.9% observations of premature and mature infants. The criteria of PPH are the extending of the posterior cornua of lateral ventricle and the absence of the interthalamus commissure in normal indexes of mass and anatomically formed brain. In pathogenesis of PPH the influence of teratogenic factors which enables to put it down to the minimal brain dysplasia is possible. PPH, though it is not of a clinical importance itself, can be favourable background for the developing of the hydrocephalus, but in the majority of the cases during postnatal period it liquidates.