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Updated: Feb 10, 2026

Dual-color Correlative Light and Electron Microscopy for the Visualization of Interactions between Mitochondria and Lysosomes
Published on: September 27, 2024
[Dual-factor correlation analysis of the distribution of morphofunctional properties of mitochondria]
Abstract:
Judging by double-factorial correlative analysis of mitochondrial morpho-functional property distribution during the treatment of organism with radioactive rays, it has been established that there is a high correlation between mitochondrial dimensions in population and known structural-functional types. To detect the force and tightness of this parameters' connection, there lists a method of double-factorial correlative analysis. The value of correlation coefficient lets assume that mitochondrial functional activity depends on mitochondrial dimensions and is described by straight regression equation. It has been established that dimension's increase is accompanied by mitochondrial functional activity decrease and vice versa, though some functionally inactivated mitochondria can have little dimensions. Thus, knowing mitochondrial dimensions in population we can detect it's functional properties and detect mitochondrial dimensions knowing the functional properties by straight regression curves.
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