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Sexual disorders in Huntington's disease

J P Fedoroff1, C Peyser, M L Franz

  • 1University of Toronto School of Medicine, Ontario, Canada.

The Journal of Neuropsychiatry and Clinical Neurosciences
|January 1, 1994
PubMed
Summary
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Sexual disorders are common in Huntington

Area of Science:

  • Neuroscience
  • Psychiatry
  • Human Sexuality

Background:

  • Huntington's disease (HD) is a neurodegenerative disorder.
  • Sexual dysfunction is a potential complication of HD.
  • Limited unbiased data exists on the prevalence and types of sexual disorders in HD patients and their partners.

Purpose of the Study:

  • To determine the frequency and nature of sexual disorders in an unbiased sample of Huntington's disease patients.
  • To assess sexual disorders in partners of Huntington's disease patients.
  • To explore potential associations between specific sexual dysfunctions and paraphilic disorders in HD patients.

Main Methods:

  • Assessed sexual disorders using DSM-III-R criteria in 39 Huntington's disease patients and 32 partners.

Related Experiment Videos

  • Analyzed the types and frequency of reported sexual disorders.
  • Investigated correlations between inhibited orgasm, increased sexual interest, and paraphilic disorders.

    • Main Results:

    • A high prevalence of sexual disorders was observed: 82% in HD patients and 66% in partners.
    • Hypoactive sexual disorder was the most common diagnosis in both groups.
    • HD patients with inhibited orgasm and increased sexual interest showed a higher incidence of paraphilic disorders.

    Conclusions:

    • Sexual disorders are highly prevalent in individuals with Huntington's disease and their partners.
    • Hypoactive sexual disorder is a significant issue for this population.
    • The co-occurrence of inhibited orgasm, increased sexual interest, and paraphilias in HD patients warrants further research into potential etiological links.