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Updated: Jul 25, 2026

Functional Cloning Using a Xenopus Oocyte Expression System
Published on: January 30, 2016
[Cloning and sequence of thyrotropin beta subunit of a teleost fish: the eel (Anguilla anguilla L.)]
C Salmon1, J Marchelidon, Y A Fontaine
1Laboratoire de Physiologie Générale et Comparée, Muséum National d'Histoire Naturelle, CNRS, URA 90, Paris, France.
Abstract:
We obtained the sequence of eel thyrotropin beta-subunit cDNA. About 1,100 bp long, it encodes a 147-amino acid protein including a 20-residue signal peptide. We analyse homologies between angTSH beta and the other known beta-subunits taking in account the ability of mammal gonadotropins (GTH) to stimulate teleost thyroid. A peptide corresponding to mammalian CAGYC (implicated in subunit association) is original and different from its eel beta GTH2 counterpart.
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