[Estimation of the effect of mitral valve correction]

From September 1958 to December 1992, 488 patients underwent mitral valve repair in Fuwai Hospital. Patients ages ranged from 49 days to 60.5 years (mean age 29.02 +/- 9.97 years). The cause of mitral valve disease was rheumatic in 415 patients (85.04%). 391 patients (80.12%) had isolated mitral valve disease and 97 patients (19.88%) had associated with aortic or tricuspid valve disease, or both. There were 167 patients (34.22%) with pure mitral stenosis, 106 patients (21.72%) with pure mitral regurgitation and 215 patients (44.06%) with both. 64.96% of the patients were in New York Heart Association (NYHA) III and IV before the operation. There were 433 patients (88.73%) with isolated mitral valve repair and 55 patients (11.27%) with mitral valve repair associated with other valve repair. The hospital mortality rate was 11.27% (7.00% after 1980). 7.39% of the patients were in NYHA III and IV after operation (P < 0.01). Follow-up was 92.38% complete and totaled 4824. 12 patient-years. The mean follow-up time was 12.3 +/- 8.83 years. The 5-year, 10-year and 20-year survival rates were 94.92%, 89.70% and 70.19%, respectively. The rate of reoperation was 4.16% (0.37%/pt-yr) and the one of thromboemboli was 5.54% (0.498%/pt-yr). The follow-up mortality and reoperation rate of rheumatic mitral valve disease were significantly higher than the other causes (P < 0.01). In hospital and follow-up results of the pure MI were better than the MS and MSI (P < 0.01). The better results were obtained in mitral annuloplasty with prosthetic valve ring.