[C-polymorphism of chromosomes in female reproductive system disorders]

Frequencies of extreme C segments of chromosomes 1, 9, and 16 were studied in patients with isolated gonadotropin deficiency (I), gonadotropin resistant ovary (I), and polycystic ovarian disease (III). Increased chromosome 9 heterochromatin was revealed for all syndromes, and increased chromosome 1 heterochromatin was revealed for groups II and III. Identical changes in heterochromatic parts of chromosomes, linked with increased heterochromatin, probably suggest a lack of specificity for the syndromes studied.