Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sensitivity analysis of relative accommodation and vergence

G K Hung1, K J Ciuffreda

  • 1Department of Biomedical Engineering, Rutgers University, Piscataway, NJ 08855-0909.

IEEE Transactions on Bio-Medical Engineering
|March 1, 1994
PubMed
Summary

The study found that the eye's accommodation and vergence systems are most sensitive to changes in crosslink gain. Understanding this sensitivity may help explain ocular dysfunctions like strabismus.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spatial frequency discrimination in anisometropic and strabismic amblyopia.

Applied optics·2010
Same author

Elevated dark adaptation thresholds in traumatic brain injury.

Brain injury·2005
Same author

Effect of cumulative nearwork on accommodative facility and asthenopia.

International ophthalmology·2003
Same author

Fixational ocular motor control is plastic despite visual deprivation.

Visual neuroscience·2003
Same author

Differential retinal-defocus magnitude during eye growth provides the appropriate direction signal.

Medical science monitor : international medical journal of experimental and clinical research·2001
Same author

A unifying theory of refractive error development.

Bulletin of mathematical biology·2000

Area of Science:

  • Ophthalmology
  • Vision Science
  • Biophysics

Background:

  • The interaction between accommodation and vergence is crucial for clear binocular vision.
  • Previous models have described the nonlinear static relationship between accommodation and vergence.
  • Understanding parameter sensitivity is key to identifying potential causes of visual dysfunction.

Purpose of the Study:

  • To perform a sensitivity analysis on a nonlinear static model of accommodation and vergence.
  • To determine how variations in model parameters affect the accommodation and vergence systems.
  • To identify which parameters have the most significant impact on normal visual function.

Main Methods:

  • A previously developed nonlinear static model of accommodation and vergence was used.

Related Experiment Videos

  • Model simulations were run with parameter values from four subjects under two conditions.
  • Key parameters including controller gains, crosslink gains, deadspace operators, and tonic levels were varied by 50% and 150%.

    • Main Results:

    • The accommodation and vergence systems showed the highest sensitivity to variations in crosslink gain (AC and CA).
    • Moderate sensitivity was observed for controller gain (ACG, VCG) and tonic levels (ABIAS, VBIAS).
    • The systems were least sensitive to changes in the deadspace operators (AE, AD, VE, VD).

    Conclusions:

    • Crosslink gain is a critical parameter influencing the stability and function of the accommodation and vergence systems.
    • Abnormalities in crosslink gain may underlie ocular dysfunctions such as strabismus.
    • The findings provide a quantitative framework for understanding the etiology of certain visual disorders.