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Nonketotic hyperosmolar coma in children

T Eidlitz-Markus1, M Nussinovitch, I Varsano

  • 1Department of Pediatrics C, Children's Medical Center of Israel, Petah Tikva.

Israel Journal of Medical Sciences
|August 1, 1994
PubMed
Summary
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Nonketotic hyperosmolar diabetic coma, a serious condition, is rare in children but successfully treated in a 12.5-year-old girl. This case highlights effective management strategies for this critical pediatric diabetic emergency.

Area of Science:

  • Pediatric Endocrinology
  • Metabolic Disorders

Background:

  • Nonketotic hyperosmolar diabetic coma (NHDC) is a severe complication of diabetes mellitus.
  • While well-documented in adults, NHDC is infrequently reported in pediatric populations.
  • This syndrome carries a significant mortality rate, ranging from 20% to 70%.

Observation:

  • A 12.5-year-old female presented with a hyperglycemic crisis.
  • Her glucose levels reached 1,800 mg/dl, indicative of severe hyperglycemia.
  • The patient experienced a nonketotic hyperosmolar diabetic coma.

Findings:

  • The case details the successful treatment and recovery of the pediatric patient.
  • A review of existing literature on pediatric NHDC cases was conducted.
  • This report adds to the limited data on NHDC in children.

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Implications:

  • Successful management of pediatric NHDC is achievable.
  • This case underscores the importance of recognizing and promptly treating NHDC in children.
  • Further research into pediatric-specific NHDC management protocols is warranted.