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Improvement of sleep apnoea due to acromegaly during short-term treatment with octreotide
G Leibowitz1, M S Shapiro, M Salameh
1Department of Endocrinology and Metabolism, Hebrew University Hadassah Medical Centre, Jerusalem, Israel.
Journal of Internal Medicine
|August 1, 1994
Abstract:
Two acromegalic patients suffering from severe obstructive sleep apnoea syndrome were treated with the long-acting somatostatin analogue octreotide. Daytime sleepiness and fatigue improved within a few days. Repeat sleep studies performed after octreotide treatment revealed more confluent sleep with a shorter duration of sleep apnoea. Nocturnal hypoxaemia improved in one patient. Octreotide might be an effective noninvasive treatment for sleep apnoea of acromegaly.