[Effect of infections on the course and effectiveness of epilepsy treatment in children]

The analysis was carried out in a group of 32 children with coexistent chronic urinary tract or respiratory infections. In 20 children an unfavourable effect of infection on the course of epilepsy was observed. Worsening of epilepsy during infection was observed mainly in children without evidence of nervous system damage with primarily generalized seizures, and in cases when the first attacks developed after protective vaccinations. The effect of urinary tract infections was particularly unfavourable. The authors put forward the hypothesis of immunological basis of exacerbation of epileptic seizures during chronic infections.