Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Neurosarcoidosis]

M Sakuta1

  • 1Department of Neurology, Japanese Red Cross Medical Center.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|June 1, 1994
PubMed
Summary

Sarcoidosis nervous system involvement, or neurosarcoidosis, affects 6.4% of patients in Japan, often impacting the central nervous system. This condition requires careful diagnosis and classification for effective management.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Tension headache: clinical treatment].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine·2001
Same author

A case of adenoid cystic carcinoma (ACC) of the breast and review of the utility of preoperative imaging diagnose.

Breast cancer (Tokyo, Japan)·2001
Same author

Effects of conditioned medium on activities of PAL, CHS, DAHP synthase (DS-Co and DS-Mn) and anthocyanin production in suspension cultures of Fragaria ananassa.

Plant science : an international journal of experimental plant biology·2001
Same author

Alexia caused by a fusiform or posterior inferior temporal lesion.

Journal of the neurological sciences·2000
Same author

Mitochondrial encephalomyopathy showing prominent microvacuolation and necrosis of intestinal smooth muscle cells: a case diagnosed by rectal biopsy.

Acta neuropathologica·1998
Same author

Reversible memory disturbance and intelligence impairment induced by long-term anticholinergic therapy.

Internal medicine (Tokyo, Japan)·1998

Area of Science:

  • Neurology
  • Immunology
  • Pathology

Context:

  • Sarcoidosis is a multisystem inflammatory disease.
  • Nervous system involvement (neurosarcoidosis) is a recognized complication.
  • Prevalence data in specific regions like Japan is crucial for understanding disease burden.

Purpose:

  • To classify neurosarcoidosis based on the location of nervous system involvement.
  • To establish diagnostic criteria for definite, probable, and possible neurosarcoidosis.
  • To highlight the underrecognized frequency of peripheral nervous system involvement.

Summary:

  • Nervous system involvement in sarcoidosis occurs in 6.4% of Japanese patients, with half experiencing central nervous system impact.
  • Neurosarcoidosis is classified into central (meningoencephalitis, granuloma, hydrocephalus, hypothalamus/pituitary) and peripheral (cranial, spinal nerves) types.
  • Diagnostic criteria include pathological proof (definite), laboratory/radiological evidence (probable), and clinical signs (possible).
  • Autopsy findings suggest cranial and spinal nerve involvement is more common than clinically apparent.

Impact:

  • Provides a structured classification and diagnostic criteria for neurosarcoidosis.
  • Emphasizes the need for increased clinical suspicion for peripheral nerve involvement in sarcoidosis.
  • Contributes to a better understanding of the epidemiology and clinical spectrum of neurosarcoidosis.

Related Experiment Videos