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Does endoscopic sphincterotomy destroy the function of Oddi's sphincter?

P M Heinerman1, A H Graf, O Boeckl

  • 1Department of Surgery, Gastroenterological Surgery, Salzburg General Hospital, Austria.

Archives of Surgery (Chicago, Ill. : 1960)
|August 1, 1994
PubMed
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Endoscopic sphincterotomy (ES) changes but does not destroy the function of Oddi's sphincter. This study compared pressure and flow variables in patients who underwent ES versus a control group.

Area of Science:

  • Gastroenterology
  • Surgical Innovation
  • Biliary System Physiology

Background:

  • Cholelithiasis is a common condition requiring intervention.
  • Endoscopic sphincterotomy (ES) is a procedure used in managing biliary diseases.
  • The impact of ES on Oddi's sphincter function requires thorough evaluation.

Purpose of the Study:

  • To assess the potential for destruction of Oddi's sphincter following endoscopic sphincterotomy (ES).
  • To investigate the functional changes in Oddi's sphincter after ES.

Main Methods:

  • A prospective, nonrandomized control trial was conducted between 1986 and 1991.
  • Ninety-one patients with cholecystolithiasis and common bile duct diseases underwent preoperative ES followed by cholecystectomy.
  • A control group of ninety-five patients with cholecystolithiasis alone underwent cholecystectomy, with pressure and flow variables measured in the common bile duct.

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Main Results:

  • No significant differences in resting pressure were observed between the ES and control groups (P < .4).
  • The maximum pressure after saline injection was significantly lower in the ES group (P < .01).
  • Normalizing time did not show a statistically significant difference between the groups (P < .375).

Conclusions:

  • Endoscopic sphincterotomy alters the function of Oddi's sphincter.
  • The functional changes observed do not indicate complete destruction of Oddi's sphincter following ES.