[Ways of realizing the immunomodulating effects of mediators]

On the process of rosette formation in CBA mice spleens, immunized by ram erythrocytes, 1) participation of hypothalamohypophyseal complex in depressive effect of ATP (high doses), 2) participation of n. vagus in stimulating effects of serotonin and ATP (low doses), 3) participation of both regulating ways in analogue dose-dependent effects of recombinant human interleukin-2, have been shown.