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Food allergy and intolerance

F H Opper1, R Burakoff

  • 1School of Medicine, State University of New York, Stony Brook.

The Gastroenterologist
|September 1, 1993
PubMed
Summary
This summary is machine-generated.

True food allergies, often immunoglobulin E-mediated, affect 10% of the US population. Diagnosis involves history, physical exams, and tests like skin prick tests and radioallergosorbent tests (RAST).

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Area of Science:

  • Immunology
  • Allergy and Immunology
  • Gastroenterology

Background:

  • Adverse reactions to foods and additives are frequent.
  • True food allergies, involving immune mechanisms, impact about 10% of the US population.
  • Immunoglobulin E-mediated allergies are most common, with anaphylaxis as a severe risk.

Purpose of the Study:

  • To review the diagnosis and treatment of food allergies.
  • To differentiate true food allergy from other adverse food reactions.
  • To highlight diagnostic methods and management strategies.

Main Methods:

  • Diagnosis relies on patient history and physical examination.
  • In vivo diagnostic methods include skin testing and food challenges.
  • In vitro testing, such as the radioallergosorbent test (RAST), is frequently utilized.

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Main Results:

  • Food allergies affect a significant portion of the population.
  • Immunoglobulin E-mediated reactions are the predominant type.
  • Systemic anaphylaxis is the most critical potential complication.

Conclusions:

  • Accurate diagnosis is crucial for effective management.
  • Identifying and avoiding specific food allergens is the primary treatment.
  • A combination of diagnostic approaches ensures appropriate patient care.