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Updated: Aug 13, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
[Therapy of migraine with special reference to sumatriptan]
1Neurologischen Abteilung, Krankenhauses der Landeshauptstadt St. Pölten.
Abstract:
A migraine attack results from an inflammatory process of intracranial blood vessels with secondly vasodilation. Sumatriptan activates vascular 5-HT1-receptors to constrict the affected vessels (12, 14) and clinical studies have shown, that it is highly effective in the treatment of migraine and cluster headache. Results from controlled, double-blind studies are discussed, comparing sumatriptan with placebo or standard treatment. Over all it produced faster and greater relief of migraine or cluster headache and was well-tolerated. Advising patients of the risk of side-effects is necessary; it is a safe treatment. Sumatriptan 100 mg tablets or 6 mg in pre-filled syringes for use with autoinjector are available, intranasal administration still needs testing.
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