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A model for fatal halothane hepatitis in the guinea pig

R C Lind1, A J Gandolfi, P M Hall

  • 1Department of Anesthesiology, College of Medicine, University of Arizona, Tucson.

Anesthesiology
|August 1, 1994
PubMed
Summary

Glutathione depletion exacerbates halothane-induced liver injury in guinea pigs. Replenishing glutathione levels protected against halothane hepatitis, establishing a new animal model for fatal liver necrosis.

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