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[Hemostasis-regulating role of nicotinic acid and its analogs]
Biulleten' Eksperimental'Noi Biologii I Meditsiny
|March 1, 1993
Abstract:
Nicotine acid and especially its analogs nicomorpholine and azethylnicotinate have ability to inhibit the thrombocytes' aggregation, inhibit thromboxane A2 biosynthesis, stimulate prostacyclin generative function of vascular wall, increase the cycle nucleotide level, have the features of calcium antagonists. This features predetermine their use for correction and healing of thromboembolic diseases and improvement of microcirculation, cerebral as well.