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Annular abscesses and GRF glue

P Stassano1, G Rispo, M Losi

  • 1Department of Cardiac Surgery, Medical School, University of Naples Federico II, Italy.

Journal of Cardiac Surgery
|May 1, 1994
PubMed
Summary
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Aortic bioprosthetic endocarditis with abscesses can be treated with valve replacement and debridement using gelatin-resorcin-formalin glue. This innovative approach offers a promising solution for complex cases, leading to asymptomatic recovery.

Area of Science:

  • Cardiovascular Surgery
  • Infectious Diseases
  • Biomaterials Science

Background:

  • Infective endocarditis complicating aortic prosthesis is a severe post-valve surgery issue.
  • Surgical correction is challenging, often necessitating complex interventions.
  • Annular abscesses present a significant hurdle in managing aortic bioprosthetic endocarditis.

Purpose of the Study:

  • To evaluate the efficacy of a surgical technique using gelatin-resorcin-formalin (GRF) glue for treating aortic bioprosthetic endocarditis with annular abscesses.
  • To assess the long-term outcomes and safety of this combined approach.

Main Methods:

  • Surgical debridement of annular abscesses and replacement of the aortic bioprosthesis.
  • Closure of abscess cavities using gelatin-resorcin-formalin (GRF) glue.

Related Experiment Videos

  • Clinical and echocardiographic follow-up of patients.

    • Main Results:

    • Successful debridement and complete sealing of abscess cavities with GRF glue in two patients.
    • Aortic valve replacement with a bioprosthesis was performed in both cases.
    • One-year follow-up revealed patients were asymptomatic with no signs of aortic incompetence.

    Conclusions:

    • Gelatin-resorcin-formalin glue is an effective adjunct for sealing annular abscesses in aortic bioprosthetic endocarditis.
    • This surgical strategy provides a viable option for complex cases, leading to favorable patient outcomes.
    • The technique shows promise for managing challenging infective endocarditis complications after aortic valve surgery.