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Updated: Aug 6, 2026

09:58
RhoC GTPase Activation Assay
Published on: August 22, 2010
Antibodies to part of the Rho antigen complex occurring in two women with Rho variants
Transfusion
|May 1, 1975
Abstract:
Two women with Rho variants are reported. Both had received transfusions and had anti-Rh antibodies. One was found to have anti-Rh-ACD and anti-Jk-a and represents a phenotype not reported previously. The other was the mother of a child with a mild hemolytic disease caused by anti-Rh-CD. Family studies of both patients showed transmission of Rh-cd but not Rh-acd. Emphasis is placed on transfusing Rho negative blood to Rho variants lacking any or all of factors Rh-A, Rh-B, Rh-C and Rh-D.
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Overview
Small GTPases - Ras and Rho
Ras and Rho are small monomeric GTPases that act downstream of receptor tyrosine kinase (RTK) and regulate various cellular processes. These GTPases switch between active and inactive states by binding to guanine nucleotides.
Three regulatory proteins control their activity:
Three regulatory proteins control their activity:
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