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Primary lung cancer invading the chest wall
1Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
Chest Surgery Clinics of North America
|February 1, 1994
Summary
Chest wall invasion in non-small cell lung cancer does not mean incurable. Surgical resection offers over 50% 5-year survival for selected patients without metastasis.
Area of Science:
- Thoracic Surgery
- Surgical Oncology
- Pulmonology
Background:
- Chest wall invasion is a common concern in non-small cell lung cancer (NSCLC).
- Historically, chest wall invasion has been associated with poor prognosis.
- Accurate preoperative staging is crucial for treatment planning.
Purpose of the Study:
- To evaluate the curability and survival outcomes for NSCLC patients with chest wall invasion.
- To identify prognostic factors influencing survival after resection.
Main Methods:
- Review of patients with NSCLC and chest wall invasion undergoing surgical resection.
- Preoperative assessment including imaging and nodal staging.
- Analysis of survival rates based on surgical complete resection and lymph node status.
Main Results:
- Complete resection is feasible for selected NSCLC patients with chest wall invasion.
- Survival rates exceed 50% at 5 years for patients without lymph node involvement undergoing en bloc resection.
- Radiotherapy and chemotherapy did not demonstrate a significant impact on survival in this cohort.
Conclusions:
- Chest wall invasion in NSCLC should not be considered a contraindication for surgical resection.
- En bloc resection of the lung and involved chest wall can achieve favorable long-term survival in select patients.
- Adjuvant therapies (radiotherapy, chemotherapy) did not improve survival in this study population.