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Comparison of the germicidal activity of prepodyne and betadine surgical scrub solutions
Abstract:
Two iodophoric surgical scrubs soaps, Prepodyne and Betadine, were evaluated for bacteriocidal activity in a modified phenol coefficient test. A standard inoculum of each of 18 species of microorganisms was mixed with a 1:8 dilution of each iodophor and subcultured after one, three, and five minutes of exposure. Complete cidal activty was exhibited by both Prepodyne and Betadine. Twenty-five subjects were tested in hand washing experiments using Betadine and Prepodyne surgical scrub solutions. Quantitative fingerprint cultures were obtained before and after hand washing. Betadine resulted in an 85.2 per cent plus or minus 24 per cent decrease; Prepodyne, and 83.6 per cent plus or minus 21 per cent decrease. It can'be concluded from this data that there is no difference in bacteriocidal effectiveness between the two scrub soaps.
Insights
Both Betadine and Prepodyne surgical scrubs demonstrated complete bactericidal activity against 18 microorganisms. Hand washing trials showed no significant difference in bacterial reduction between these two effective iodophor surgical soaps.
Area of Science:
- Microbiology
- Infectious Diseases
- Surgical Hygiene
Background:
- Surgical site infections remain a significant concern in healthcare settings.
- Effective surgical scrubs are crucial for reducing microbial load on hands.
- Iodophors are commonly used antiseptics in surgical preparations.
Purpose of the Study:
- To compare the bactericidal efficacy of two iodophoric surgical scrub soaps: Betadine and Prepodyne.
- To evaluate the reduction in microbial counts on hands after using each surgical scrub.
Main Methods:
- A modified phenol coefficient test was employed to assess bactericidal activity against 18 microbial species.
- Quantitative fingerprint cultures were performed on 25 subjects before and after hand washing with Betadine and Prepodyne.
Main Results:
- Both Betadine and Prepodyne exhibited complete bactericidal activity against all tested microorganisms within 1-5 minutes.
- Hand washing with Betadine reduced bacterial counts by 85.2% ± 24%, while Prepodyne achieved an 83.6% ± 21% reduction.
Conclusions:
- There is no statistically significant difference in bactericidal effectiveness between Betadine and Prepodyne surgical scrub soaps.
- Both evaluated iodophoric surgical scrubs are effective in reducing microbial contamination on hands.