Related Experiment Videos
Cytogenetic studies in five patients with Sézary syndrome
F Solé1, S Woessner, T Vallespi
1Laboratori de Citologia Hematològica, Hospital Central L'Aliança, Barcelona, Spain.
Cancer Genetics and Cytogenetics
|July 15, 1994
Abstract:
A cytogenetic study was performed in five patients with Sézary syndrome. Metaphases were obtained from a phytohemagglutinin-stimulated lymphocyte culture. The five patients showed abnormal karyotypes. The chromosomes preferentially involved in numerical aberrations were chromosomes 10 (monosomy) and 13 (monosomy); involved in structural changes were chromosomes 1, 2, 4, 6, and 14. In our series, all patients showed progression of the disease.