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[The effect of age on parameters of thyroid function]
1Zakład Medycyny Nuklearnej AM, Lublinie.
Endokrynologia Polska
|January 1, 1993
Summary
Thyroid gland function and hormone metabolism change throughout human life. These age-related thyroid changes are most significant from birth through maturity and again in elderly individuals.
Area of Science:
- Endocrinology
- Human Physiology
- Thyroidology
Context:
- Thyroid hormones regulate metabolism and development across all life stages.
- Understanding age-related physiological changes is crucial for health assessment.
Purpose:
- To investigate the impact of aging on thyroid gland function and hormone metabolism.
- To analyze thyroid hormone levels (thyroxine, triiodothyronine, TSH) across the human lifespan.
Summary:
- Radioimmunoassay determined thyroid hormone levels in 1350 euthyroid individuals aged 3 days to 81 years.
- Both thyroid hormone secretion and peripheral metabolism show age-dependent alterations.
- The relationship between age and thyroid function is most pronounced in early life and in the elderly.
Impact:
- Provides a comprehensive overview of thyroid function across the human lifespan.
- Highlights critical periods of thyroid function changes, informing clinical practice and research.
- Establishes normative data for thyroid hormones in relation to age.