Toxins that inhibit host protein synthesis
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1Department of Microbiology and Immunology, University of Rochester, School of Medicine and Dentistry, New York 14642.
Methods in Enzymology
|January 1, 1994
Abstract:
Methods have been described that are sufficient to determine if a bacterial protein toxin is a selective inhibitor of eukaryotic protein synthesis, and, if so, which part of the overall process is affected. More defined assays are presented for studying the steps of peptide elongation as this is where such toxins have been shown to act.