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[Treatment of severe forms of Langerhans cell histiocytosis]
1Service d'hématologie pédiatrique et de transplantation de moelle osseuse, hôpital Debrousse, Lyon, France.
Langerhans cell histiocytosis is a non malignant disorder of immune regulation. Patients with multisystem disease and organ dysfunction are considered to have a poor prognosis, and particularly children younger than 2 years of age. Clinical trials using human alpha-interferon, cyclosporine A and bone marrow transplantation have been reported recently.
Langerhans cell histiocytosis is a non malignant disorder of immune regulation. Patients with multisystem disease and organ dysfunction are considered to have a poor prognosis, and particularly children younger than 2 years of age. Clinical trials using human alpha-interferon, cyclosporine A and bone marrow transplantation have been reported recently.