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The pathologist and the residual tumor (R) classification
1Chirurgische Klinik, Universität Erlangen, Germany.
Pathology, Research and Practice
|February 1, 1994
Summary
The R classification system, established in 1987, assesses residual tumor after cancer treatment. It is crucial for predicting patient prognosis and guiding treatment decisions.
Area of Science:
- Oncology
- Pathology
Background:
- The R classification system, adopted by the UICC in 1987, categorizes the presence or absence of residual tumor post-treatment.
- Residual tumor can manifest as local recurrence or distant metastases, impacting patient outcomes.
Purpose of the Study:
- To detail the procedures for pathological R classification on resection specimens across various organs.
- To highlight the clinical significance of the R classification as a prognostic indicator.
Main Methods:
- The R classification integrates clinical and pathological findings.
- Pathological examination of resection margins is essential for accurate classification.
- New methods include imprint cytology, examination of ascites, and bone marrow biopsy.
Main Results:
- R0 indicates complete remission or resection for cure.
- R1 signifies microscopic residual tumor.
- R2 denotes macroscopic residual tumor.
Conclusions:
- The R classification is a vital prognostic tool in cancer management.
- Further validation is needed for emerging methods in R classification.