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Insulin and hypertension: are they related?
W P Meehan1, C H Darwin, N B Maalouf
1Department of Medicine, University of Southern California Medical School, Los Angeles 90038.
Przeglad Lekarski
|January 1, 1994
Abstract:
It has been postulated that insulin resistance and the concomitant compensatory hyperinsulinemia contribute to the pathogenesis of hypertension; possible by stimulating the sympathetic nervous system, promoting renal sodium reabsorption, modulating cation transport, and/or stimulating vascular smooth muscle hypertrophy. The purpose of this article is to present a comprehensive up-to-date review of the literature and critically examine the insulin resistance-hyperinsulinemia-hypertension hypothesis.