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[Diabetic coma. A report of 752 cases between 1931 and 1973]
MMW, Munchener Medizinische Wochenschrift
|April 18, 1975
Summary
Diabetic coma mortality rates, particularly in ketoacidotic cases, were influenced by factors like obesity and infections. Insulin therapy was associated with the lowest lethality in diabetic coma patients.
Area of Science:
- Endocrinology
- Internal Medicine
- Medical History
Background:
- Diabetic coma represents a severe complication of diabetes mellitus.
- Understanding historical trends in diabetic coma is crucial for contemporary diabetes management.
Purpose of the Study:
- To investigate the characteristics and lethality of diabetic coma over a 40-year period.
- To identify risk factors associated with increased mortality in diabetic coma patients.
Main Methods:
- Retrospective analysis of 752 cases of diabetic coma from 1931 to 1973.
- Data collected included type of coma, age, sex, blood sugar levels, body type, prior therapy, and infection status.
Main Results:
- Blood sugar and patient age at the time of coma increased significantly from 1931-1940 to 1971-1973.
- Higher mortality was observed in patients with obesity, women, and those with infections, especially in multiple organs.
- Insulin-treated patients exhibited the lowest lethality rate (14.6%).
Conclusions:
- Diabetic coma characteristics and associated mortality factors have evolved over four decades.
- Obesity, female sex, and concurrent infections significantly increase the risk of death in diabetic coma.
- Effective diabetes management, including insulin therapy, is critical in reducing diabetic coma lethality.