A perfusion phantom for the evaluation of ultrasound contrast agents

A renal dialysis cartridge was adapted for use as a perfusion phantom for the investigation of ultrasound contrast agents. In preliminary studies using this phantom, it was possible to visualise the effects of introduction of contrast material into the system, on both real-time and colour Doppler imaging. It was also possible to make quantitative measurements relating to the backscatter and attenuation properties of the contrast material. The method of adapting the dialysis cartridge is economical and convenient, and should provide a useful in vitro model in which to evaluate and compare ultrasound contrast agents.